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杜会枝
[ 发布日期:2019-02-24  ] 【返回

杜会枝,女,教授,硕士生导师。1974年生于山西省太谷县。2006年于山西大学分子科学研究所获理学博士学位。20093月至20131月,于美国三所大学做博士后研究工作。20168月至11月,获山西省留学办资助于英国利兹大学(University of Leeds)进行公派高级学术访问。主持或参与完成了多项国家级和省部级科研项目。

主要研究方向:中药神经药理,生物无机化学。

研究兴趣:探索山西道地中药材在预防、改善及治疗神经退行性疾病中的作用机制。

主要技术:化学方法、分子生物学技术结合电生理记录。


近期主持科研项目:

  1. 国家自然科学基金(81403130)

  2. 山西省回国留学人员科研资助项目(2017-021)

  3. 山西省自然科学基金(2018D01D121290)

  4. 教育部第48批留学回国人员科研启动基金

  5. 山西省人社厅2013山西省留学回国科技活动择优项目

  6. 农业部委托研究项目


近期发表论文:

  1. J Zhao, ... Huizhi Du*. Is the weight-reducing effect of aerobic exercise in mice mediated by a regulatory effect of SFRS10 on alternative splicing of PKCδI pre-mRNA? Sci Sport, 2020, 35: 50-4.

  2. Y Tian, Huizhi Du, L Zhang*. Effects of Picking Time and Drying Methods on Contents of Eight Flavonoids and Antioxidant Activity of Leaves of Diospyros lotus L. J Food Meas Charact, 2020, in press.

  3. 周立锦, 董哲, 杜会枝*. 低共熔溶剂在中药成分提取中的研究进展. 中草药, 2020, 51(1): 236-44.

  4. L Chen, ... Huizhi Du*. Forsythiaside prevents β-amyloid-induced hippocampal slice injury by upregulating 2-arachidonoylglycerol via cannabinoid receptor 1-dependent NF-κB. Neurochem Int, 2019, 125: 57-66.

  5. Y Li, ... Huizhi Du*. Different effects of Forsythia suspensa metabolites on bovine serum albumin (BSA). Spectrochim Acta A Mol Biomol Spectrosc, 2019, 214: 309-19.

  6. B Wu, ... Huizhi Du*. Comparison of the quenching effects of two main components of ziziphi spinosae semen on serum albumin fluorescence. J Fluoresc, 2019, 29: 1113-23.

  7. H Sun*, L Kong, Huizhi Du, et al. Benefits of Pseudomonas poae s61 on Astragalus mongholicus growth and bioactive compound accumulation under drought stress. J Plant Int, 2019, 14(1): 205-12.

  8. Y Yan, Huizhi Du, et al. Determination of five neurotransmitters in the rat brain for the study of the hypnotic effects of Ziziphi Spinosae Semen aqueous extract on insomnia rat model by UPLC-MS/MS. Chin J Nat Med, 2019, 17(7): 551-60.

  9. X Yan, ... Huizhi Du*. Study of the interactions of forsythiaside and rutin with acetylcholinesterase (AChE). Int J Biol Macromol, 2018, 119: 1344-52.

  10. L Lin, Huizhi Du*. An anthraquinone compound and its protective effects against homocysteine-induced cytotoxicity and oxidative stress. Spectrochim Acta A Mol Biomol Spectrosc, 2018, 202: 314-8.

  11. L Chen, ... Huizhi Du*. Comparison of neuroprotective effect of Forsythia suspensa leaf extract and forsythiaside one of its metabolites. Nat Prod Res, 2018, 32(22): 2705-8.

  12. X Yan, et al, Huizhi Du*. Protective effects of Forsythoside A on amyloid beta-induced apoptosis in PC12 cells by downregulating acetylcholinesterase. Eur J Pharmacol, 2017, 810: 141-8.

  13. H Sun, ... Huizhi Du. Characterization of root-associated microbiota in medicinal plants Astragalus membranaceus and Astragalus mongholicus. Ann Microbiol, 2017, 67: 587-99.

  14. G Zhang*, Huizhi Du, et al. A reversible fluorescent pH-sensing system based on the one-pot synthesis of nature silk fibroin-capped copper nanoclusters. J Mater Chem C, 2016, 4: 3540-5.

  15. J Chen, ... Huizhi Du. Deep eutectic solvent-based microwave-assisted method for extraction of hydrophilic and hydrophobic components from Radix Salviae miltiorrhizae. Molecules, 2016, 21(10): 1383.

  16. Q Liu, Huizhi Du, et al. Design of ratiometric emission probe with visible light excitation for determination of Ca2+ in living cells. Anal Chem, 2014, 86(16): 8025-30.

  17. Huizhi Du, et al. Neuregulin-1 impairs the long-term depression of hippocampal inhibitory synapses by facilitating the degradation of endocannabinoid 2-AG. J Neurosci, 2013, 33(38): 15022-31.

  18. Huizhi Du, et al. Inhibition of COX-2 expression by 2-AG is mediated via PPAR-γ. Brit J Pharmacol, 2011, 163(7): 1533-49.

  19. Huizhi Du, et al. Enhancement of lanthanum (III) on sodium currents in acutely isolated hippocampal CA1 neurons of rat. Neurochem Res, 2009, 34(9): 1562-7.

  20. Huizhi Du, et al. Effects of 3-benzidino-6-phenylpyridazine, as an acetylcholinesterase inhibitor, on outward potassium current in acutely isolated rat hippocampal pyramidal neurons. Toxicol Lett, 2008, 181(2):104-11.


授权专利:

  1. 杜会枝,林利霞。1,4-二丙烯酸酯蒽-9,10-二酮及其制备方法和应用。专利号: ZL201710041954.0

  2. 杜会枝。一种简便膜片钳记录槽。专利号:ZL201720400068.8


联系方式:

电 话:13485303893

Emailduhuizhi@sxu.edu.cn

单 位:山西大学分子科学研究所

地 址:山西省太原市坞城路92

邮 编:030006


友情链接: 北京大学 清华大学 南京大学 中科院山西煤化所 太原理工大学 中北大学
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