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研究人员

阴彩霞


阴彩霞 1978. 4. 女,博士,山西大学分子科学研究所教授,博导,山西大学化学化工学院副院长。研究方向:化学生物学。先后在J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Chem. Soc. Rev.、Anal. Chem.、Org. Lett.、TheranosticsSens. Actuators BJ. Mater. Chem. B中国科学:化学等SCI期刊发表论文150余篇,被SCI他引4000余次,高被引6篇。参与出版外文著作1部。先后主持国家自然科学基金4项,以及多项省级项目。多次应邀参加国内外学术会议并做报告。目前担任国内一些期刊编委:中国化学快报、大学化学、无机化学学报等。曾获山西省自然科学三等奖(2015),以及三晋英才(2019)等山西省多项人才称号。已经培养多名研究生,荣获山西省研究生教育优秀导师(2018)。

学习与工作经历:

2000/09 2005/07,山西大学分子科学研究所,硕博连读

1996/09 2000/07,山西大学化学系,学士

2016/08 至今,分子科学研究所/山西大学化学化工学院,教授

2014/09 2016/07,美国密苏里大学化学系,访问学者

2009/11 2014/08,山西大学分子科学研究所,教授

2007/09 2009/10,山西大学分子科学研究所,副教授

2006/08 2007/07,台湾大学化学系,博士后

2005/07 2006/07,山西大学分子科学研究所,副教授

讲授课程:中级无机化学

研究方向:化学生物学

主持科研项目:

1. 国家自然科学面上基金,2018-2021;

2. 国家自然科学面上基金,2015-2016

3. 国家自然科学面上基金,2011-2013;

4. 国家自然科学青年基金,2008 -2010。


代表性论文:

1. Yutao Yang, Tingting Zhou, Ming Jin, Keyan Zhou, Dandan Liu, Xue Li, Fangjun Huo, Wei Li, Caixia Yin* Thiol−Chromene “Click” Reaction Triggered Self-Immolative for NIR Visualization of Thiol Flux in Physiology and Pathology of Living Cells and Mice, J. Am. Chem. Soc., 2020, 142, 1614−1620.

2. Weijie Zhang, # Fangjun Huo, # Yongkang Yue, Yongbin Zhang, Jianbin Chao, Fangqin Cheng, Caixia Yin*, Heat Stroke in Cell Tissues Related to Sulfur Dioxide Level Is Precisely Monitored by Light-Controlled Fluorescent Probes, J. Am. Chem. Soc., 2020, 142, 3262-3268.

3. Weijie Zhang, # Fangjun Huo, # Fangqin Cheng, Caixia Yin*, Employing an ICT-FRET Integration Platform for the Real-Time Tracking of SO2 Metabolism in Cancer Cells and Tumor Models, J. Am. Chem. Soc., 2020, 142, 6324−6331.

4. Ying Wen, Fangjun Huo, Junping Wang, Caixia Yin*, Multicolor Fluorescence Based on FRET Regulated by Functional Peptides To Screen High Metastatic Potential Cancer Cells, Anal. Chem., 2019, 91, 15057−15063.

5. Kangming Xiong, Fangjun Huo, Jianbin Chao, Yongbin Zhang, Caixia Yin*, Colorimetric and NIR Fluorescence Probe with Multiple Binding Sites for Distinguishing Detection of Cys/Hcy and GSH in Vivo, Anal. Chem., 2019, 91, 1472−1478.

6. Yongkang Yue, Fangjun Huo, Fangqin Cheng, Xijing Zhu, Tendai Mafireyi, Robert M. Strongin *, Caixia Yin *, Functional synthetic probes for selective targeting and multi-analyte detection and imaging, Chem. Soc. Rev., 2019, 48, 4155−4177.

7. Weijie Zhang, Fangjun Huo, Caixia Yin*, Photocontrolled Single-/Dual-Site Alternative Fluorescence Probes Distinguishing Detection of H2S/SO2 in Vivo, Org. Lett., 2019, 21, 5277−5280.

8. Yongkang Yue#, Fangjun Huo#, Ping Yue, Xiangming Meng, James C. Salamanca, Jorge O. Escobedo, Robert M. Strongin, Caixia Yin*, In situ lysosomal cysteine specific targeting and imaging during dexamethasone-induced apoptosis, Anal. Chem., 2018, 90, 7018−7024.

9. Yongkang Yue#, Fangjun Huo#, Peng Ning, Yongbin zhang, Jianbin Chao, Xiangming Meng*, Caixia Yin,* Dual-site fluorescent probe for visualizing the metabolism of Cys in living cells, J. Am. Chem. Soc., 2017, 139, 3181−3185.

10. Caixia Yin*, Kangming Xiong, Fangjun Huo, James C. Salamanca, Robert M Strongin*, Fluorescent probes with multiple binding sites for the discrimination of Cys, Hcy, and GSH, Angew. Chem. Int. Ed., 2017, 56, 13188−13198.

11. Yongkang Yue#, Fangjun Huo#, Xiaoqi Li, Ying Wen, Tao Yi*, James Salamanca, Jorge O. Escobedo, Robert M. Strongin*, Caixia Yin*, pH-Dependent fluorescent probe that can be tuned for cysteine or homocysteine, Org. Lett., 2017, 19, 82−85.

12. Weijie Zhang, Tao Liu, Fangjun Huo, Peng Ning, Xiangming Meng, Caixia Yin*, Reversible ratiometric fluorescent probe for sensing bisulphate/H2O2 and its application in zebrafish, Anal. Chem., 2017, 89, 8079−8083.

13. Ying Wen, Weijie Zhang, Tao Liu, Fangjun Huo, Caixia Yin*, Pinpoint diagnostic kit for heat stroke by monitoring lysosomal pH, Anal. Chem., 2017, 89, 11869−11874.

14. Yong kang Yue, Fangjun Huo, Jianbin Chao, Yongbin Zhang, Ramón Martínez-Máñez*, Caixia Yin*, Curcumin–basedenhanced SNAr” promoted ultrafast fluorescent probe for thiophenols detection in aqueous solution and in living cells, Anal. Chem., 2016, 88, 10499−10503.

15. Caixia Yin, Gin-Chen Huang, Ching-Kuo Kuo, Ming-Dung Fu, Hao-Cheng Lu, Jhih-Hong Ke, Kai-Neng Shih, Yi-Lin Huang, Gene-Hsiang Lee, Chen-Yu Yeh, Chun-hsien Chen*, Shie-Ming Peng*,Extended Metal-Atom Chains with an Inert Second Row Transition Metal: [Ru5(μ5-tpda)4X2] (tpda2# = tripyridyldiamido dianion, X = Cl and NCS), J. Am. Chem. Soc., 2008, 130, 10090–10092


授权专利:

阴彩霞 李晓琪 霍方俊,一种检测谷胱甘肽的试剂及其合成方法和应用,国家发明专利,ZL201710188865.9, 授权日期:2019.9.24;

阴彩霞 熊康明 霍方俊,一种荧光检测次氯酸的方法,国家发明专利,ZL201710004579.2,授权日期:2019.7.23;

阴彩霞 张慧芳 霍方俊,一种Ho3+检测试剂及其制备方法和应用,国家发明专利,ZL201611021072.X,授权日期:2019.7.23;

阴彩霞 刘涛 霍方俊,一种三苯胺双吲哚碘盐及其合成方法和应用,国家发明专利,ZL201610255378.5,授权日期:2019.4.2;

阴彩霞 李晓琪 霍方俊,一种SO32-/HSO3-检测试剂及其合成方法和应用,国家发明专利,ZL201611030085.3, 授权日期2019.1.25。


联系方式
地址:太原市坞城路92号
单位:山西大学分子科学研究所
邮编:030006
电话: 0351-7010699
eMail: yincx@sxu.edu.cn