杜会枝，女，博士，教授，博士生导师，省委联系服务的专家。山西省太谷县人。2006年获理学博士学位。2009年3月至2013年1月，于美国（Louisiana State University，Howard University，Augusta University）做博士后研究工作。2016年8月至11月于英国Leeds University进行省公派高级学术访问。主持或参与完成多项国家级和省部级科研项目。

主要研究方向：中药神经药理，无机材料化学。

近期主持的科研项目：

1. 国家自然科学基金（81403130）

2. 山西省自然科学基金（2018D01D121290，202303021211015）

3. 教育部第48批留学回国人员科研启动基金

4. 山西省人社厅2013山西省留学回国科技活动择优项目

5. 山西省回国留学人员科研资助项目（2017-021）

6. 农业部委托研究项目

7. 山西医科大学细胞生理学教育部重点实验室开放基金项目

8. 横向项目

近期发表的学术论文（部分）：

1. Conghuan Lin, Huizhi Du^*. Interactions between forsythoside E and two cholinesterases at the different conditions: fluorescence sections.  Methods Appl Fluoresc , 2024, 12: 025003.

2. Guocui Liang, Chengxia Gao, Liwei Zhang, Huizhi Du^*. Combination of tenuigenin-based  Polygala tenuifolia Willd. root extract and forsythoside A improved Alzheimer's Disease.  Nat Prod Res , 2024,  DOI: 10.1080/14786419.2024.2332945.

3. Chengxia Gao, Huizhi Du^*. Different effects of forsythoside E on acetylcholinesterase and butyrylcholinesterase by fluorescent spectroscopy.  J Applied Spectroscopy , 2022, 89 (3): 559-66.

4. Li Dang, ... Huizhi Du^*. The enhancement effects of forsythoside E on serum albumin fluorescence under the simulated physiological conditions.  Spectroscopy , 2022, 37 (5): 20-7.

5. Chengxia Gao, Huizhi Du^*. The interaction between two metabolites of  Polygala tenuifolia and cholinesterases.  Protein Pep  tide Lett , 2022, 29, 1051-60.

6. 杜会枝^*, 马红. 连翘神经药理作用的研究进展.  中国药学杂志 , 2021, 56(7): 25-9.

7. Jinfeng Zhao, ... Huizhi Du^*. Humanin protects cortical neurons from calyculin A-induced neurotoxicities by increasing PP2A activity and SOD.  Int J NeuroScience , 2021, 131(6): 527-35.

8. Qin Zhang, ... Huizhi Du^*. Deep eutectic solvents improve the stability of forsythoside A.  J Food Saf , 2021, 41, e12907.

9. Yan Yan, ... Huizhi Du^*. Metabolic profile and underlying antioxidant improvement of Ziziphi Spinosae Folium by human intestinal bacteria.  Food Chem , 2020, 320: 126651-9.

10. Jinfeng Zhao, ... Huizhi Du^*. Is the weight-reducing effect of aerobic exercise in mice mediated by a regulatory effect of SFRS10 on alternative splicing of PKCδI pre-mRNA?  Sci Sport , 2020, 35: 50-4.

11. 周立锦, ... 杜会枝^*. 低共熔溶剂在中药成分提取中的研究进展.  中草药 , 2020, 51(1): 236-44.

12. Liqing Chen, ... Huizhi Du^*. Forsythiaside prevents β-amyloid-induced hippocampal slice injury by upregulating 2-arachidonoylglycerol via cannabinoid receptor 1-dependent NF-κB.  Neurochem Int , 2019, 125: 57-66.

13. Yu Li, ... Huizhi Du^*. Different effects of  Forsythia suspensa metabolites on bovine serum albumin (BSA).  Spectrochim Acta A Mol Biomol Spectrosc , 2019, 214: 309-19.

14. Baoai Wu, ... Huizhi Du^*. Comparison of the quenching effects of two main components of ziziphi spinosae semen on serum albumin fluorescence.  J Fluoresc , 2019, 29: 1113-23.

15. Xiaojuan Yan, ... Huizhi Du^*. Study of the interactions of forsythiaside and rutin with acetylcholinesterase (AChE).  Int J Biol Macromol , 2018, 119: 1344-52.

16. Lixia Lin, Huizhi Du^*. An anthraquinone compound and its protective effects against homocysteine-induced cytotoxicity and oxidative stress.  Spectrochim Acta A Mol Biomol Spectrosc , 2018, 202: 314-8.

17. Liqing Chen, ... Huizhi Du^*. Comparison of neuroprotective effect of Forsythia suspensa leaf extract and forsythiaside one of its metabolites.  Nat Prod Res , 2018, 32(22): 2705-8.

18. Xiaojuan Yan,  et al , Huizhi Du^*. Protective effects of Forsythoside A on amyloid beta-induced apoptosis in PC12 cells by downregulating acetylcholinesterase.  Eur J Pharmacol , 2017, 810: 141-8.

19. Guomei Zhang, Huizhi Du,  et al . A reversible fluorescent pH-sensing system based on the one-pot synthesis of nature silk fibroin-capped copper nanoclusters.  J Mater Chem C , 2016, 4: 3540-5.

20. Qiaoling Liu, Huizhi Du,  et al . Design of ratiometric emission probe with visible light excitation for determination of Ca²⁺ in living cells.  Anal Chem , 2014, 86(16): 8025-30.

21. Huizhi Du,  et al . Neuregulin-1 impairs the long-term depression of hippocampal inhibitory synapses by facilitating the degradation of endocannabinoid 2-AG.  J Neurosci , 2013, 33(38): 15022-31.

22. Huizhi Du,  et al . Inhibition of COX-2 expression by 2-AG is mediated via PPAR-γ.  Brit J Pharmacol , 2011, 163(7): 1533-49.

近期的授权专利：

1. 杜会枝, 董哲. 一种提高连翘酯苷A稳定性的方法. 授权日期: 2021.3, 授权专利号: ZL201910080681X。

2. 杜会枝, 董哲. 一种连翘抗炎抗氧化成分的提取方法. 授权日期: 2020.12, 授权专利号: ZL201810077916.5。

3. 杜会枝, 林利霞. 1,4-二丙烯酸酯蒽-9,10-二酮及其制备方法和应用. 授权日期: 2019.9, 授权专利号: ZL201710041954.0。

4. 杜会枝. 一种简便膜片钳记录槽. 授权日期: 2017.12, 授权专利号：ZL201720400068.8。

联系方式：

Email：duhuizhi@sxu.edu.cn

单 位：山西大学分子科学研究所

地 址：山西省太原市小店区坞城路92号

邮 编：030006