袁彩霞,女,理学博士,教授,博士生导师。2001年毕业于山西大学化学系,获理学学士学位,2004年获山西大学理学硕士学位,并留校工作,2009年获山西大学理学博士学位,博士毕业论文荣获2009年度山西省优秀论文,2014年获国家留学基金资助赴美国科罗拉多大学访学一年,2018年11月赴北卡罗来纳大学夏洛特分校进行学术交流,同年入选山西省“三晋英才”支持计划。主持国家自然科学基金项目(Nos. 21471092 & 21001070)和山西省自然科学基金项目(Nos. 2011021006-2 & 201901D111014)4项,参与各类基金10余项;在国内外学术期刊发表SCI论文50多篇,获得国家发明专利授权8项,以第四完成人获山西省科学技术奖自然科学二等奖1项。
研究工作:
主要从事配位化学、生物无机化学和主族金属结构化学的研究。目前研究方向包括:
1、 过渡金属配合物设计合成及其生物活性研究;
2、 有机或金属有机分子对过渡金属的荧光识别研究;
3、 多原子分子中主族金属的成键特性研究。
近期代表性研究论文:
1、 Caixia Yuan, Weirong Wang, Jianwei Wang, Xinhua Li, Yanbo Wu, Shaodong Li, Liping Lu, Miaoli Zhu, Shu Xing, Xueqi Fu, Potent and selective PTP1B inhibition by a platinum(ii) complex: possible implications for a new antitumor strategy, Chem. Commun. 2020, 56, 102–105.
2、 Lixia Lin, Liping Lu, Ran Du, Caixia Yuan, Miaoli Zhu, Xueqi Fu, Shu Xing, A Ce(iii) complex potently inhibits the activity and expression of tyrosine phosphatase SHP-2, Dalton Trans, 2019, 48(47), 17973-17682.
3、 Xinhua Li, Caixia Yuan, Liping Lu, Miaoli Zhu, Shu Xing, Xueqi Fu, Exploration of Zinc(II) Complexes as Potent Inhibitors Against Protein Tyrosine Phosphatase 1B, Chem. Res. Chin. Univ., 2019, 35(2), 186-192.
4、 Xuefeng Zhao, Caixia Yuan, Sidian Li, Yanbo Wu, Xiaotai Wang, Simulating the effect of a triple bond to achieve the shortest main group metal-metal distance in diberyllium complexes: a computational study, Dalton Trans., 2018, 47(41),14462-14467.
5、 Shaodong Li, Liping Lu, Miaoli Zhu, Caixia Yuan, Sisi Feng, A bifunctional chemosensor for detection of volatile ketone or hexavalent chromate anions in aqueous solution based on a Cd(II) metal-organic framework, Sensors and Actuators B. 2018, 258, 970–980.
6、 Caixia Yuan, Shiyang Li, Yanbo Wu, Liping Lu, Miaoli Zhu, Zn(II)-selective and sensitive fluorescent chemosensor based on stericconstrains and inhibition of ESIPT, Sensors and Actuators B. 2017, 242, 1035–1042.
7、 Yuqi Jia, Liping Lu, Miaoli Zhu, Caixia Yuan, Shu Xing, Xueqi Fu, A dioxidovanadium (V) complex of NNO-donor Schiff base as a selective inhibitor of protein tyrosine phosphatase 1B: Synthesis, characterization, and biological activities, Eur. J. Med. Chem. 2017, 28, 287-292.
8、 Yuqi Jia, Liping Lu, Caixia Yuan, Sisi Feng, Miaoli Zhu, Aspartate aminotransferase is potently inhibited by copper complexes: Exploring copper complex-binding proteome, J. Inorg. Biochem. 2017, 170, 46–54.
9、 Jia-Jia Li, Yuewen Mu, Xinxin Tian, Caixia Yuan, Yan-Bo Wu, Qiang Wang, Debao Li, Zhi-Xiang Wang and Si-Dian Li, Zigzag double-chain C–Be nanoribbon featuring planar pentacoordinate carbons and ribbon aromaticity, J. Mater. Chem. C 2017, 5, 408-414.
10、 Caixia Yuan, Xinyu Liu, YanboWu, Liping Lu , Miaoli Zhu, A triazole Schiff base-based selective and sensitive fluorescent probe for Zn2+: A combined experimental and theoretical study, Spectrochim. Acta A, 2016, 154, 215–219.
11、 Caixia Yuan, Xue-Feng Zhao, Yan-Bo Wu, Xiaotai Wang, Ultrashort Beryllium-Beryllium Distances Rivalling Those of Metal-Metal Quintuple Bonds Between Transition Metals, Angew. Chem. Int. Ed. 2016, 55, 15651-15655.
12、 Caixia Yuan, Yan-BoWu, Xiaotai Wang, N-heterocyclic carbene-stabilized homoatomic lithium(0) complexes with a lithium–lithium covalent bond: A theoretical design and characterization, Inorg. Chem. Commun. 2016, 63, 61–64.
13、 Xiang Wang, Qiang Wang, Caixia Yuan, Xue-Feng Zhao, Jia-Jia Li, Debao Li, Yan-Bo Wu, Xiaotai Wang, The degree of p electron delocalization and the formation of 3D-extensible sandwich structures, Phys. Chem. Chem. Phys. 2016, 18, 11942-11950.
14、 Xue-Feng Zhao, Cai-Xia Yuan, Xiang Wang, Jia-Jia Li, Yan-Bo Wu, Xiaotai Wang, Computational Desian of Organometallic Oligomers Featuring 1,3-Metal-Carbon Bonding and Planar Tetracoordinate Carbon Atoms, J. Comput. Chem. 2016, 37, 296-303.
部分授权专利:
1、 卢丽萍,高敏,袁彩霞,一种席夫碱钯配合物及其制备方法和应用,专利号,ZL201610 874351.4。
2、 李艳红,卢丽萍,袁彩霞,丝氨酸N衍生物的金属锌配合物及其制备方法和应用,专利号,ZL201510297658.8。
3、 袁彩霞,卢丽萍,朱苗力,吴艳波,一种席夫碱铂配合物及其制备方法和应用,专利号,ZL201510229474.8。
4、 袁彩霞,卢丽萍,朱苗力,吴艳波,一种1,2,,4-**席夫碱锌配合物及其制备方法和应用,专利号,ZL201510345077.7。
5、 袁彩霞,吴艳波,朱苗力,卢丽萍,一种氨基萘酚类席夫碱化合物及其制备方法和应用,专利号,ZL201310164901.X。
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联系方式:
地址:太原市坞城路92号
单位:山西大学分子科学研究所
邮编:030006
手机:13513634694
电子邮箱:cxyuan@sxu.edu.cn