岳永康，男，1992年生。理学博士，副教授，博士研究生导师，山西省优青，山西省高校优秀青年学术带头人。2013年7月毕业于忻州师范学院，获理学学士学位。2018年7月毕业于山西大学分子科学研究所，获理学博士学位，留所工作。

主要研究方向：

荧光染料与生物成像

主持科研项目：

1. 山西省优秀青年基金（25万元，202303021224003，2024.1——2026.12）

2. 国家自然科学基金面上项目（54万元，22277069，2023.1——2026.12）

3. 国家自然科学基金青年科学基金项目（26万元，21907062，2020.1——2022.12）

4. 山西省高校优秀青年学术带头人（20万元，2019，2019.9——2022.9）

5. 山西省高等学校科技创新项目（3万元，2019L0031，2019.9——2022.9）

代表性论文：

1. Yongkang Yue, Tingting Zhao, Zhou Xu, Weijie Chi, Xiaojun Chai, Jiahong Ai, Jiawei Zhang, Fangjun Huo, Robert M. Strongin, Caixia Yin*, Enlarging the Stokes shift by weakening the p-conjugation of cyanines for high signal-to-noise ratiometric imaging, Adv. Sci., 2023, 2205080.

2. Yongkang Yue, Tingting Zhao, Kaiqing Ma, Fangjun Huo, Caixia Yin*, Endogenous cysteine fluorescence monitoring and its deployment in tumour demarcation, Chem. Commun., 2022, 58, 2311−2314.

3. Yongkang Yue, Tingting Zhao, Yuting Wang, Kaiqing Ma, Xingkang Wu, Fangjun Huo, Fangqin Cheng, Caixia Yin*, HSA-Lys-161 covalent bound fluorescent dye for in vivo blood drug dynamic imaging and tumor mapping, Chem. Sci., 2022, 13, 218−224.

4. Kaiqing Ma,# Yongkang Yue,# Lingling Zhao, Jianbin Chao, Caixia Yin*, A sequentially activated bioluminescent probe for observation of cellular H2O2 production induced by cysteine, Chem. Commun., 2021, 57, 10015-10018.

5. Yongkang Yue, Fangjun Huo, Caixia Yin*, The chronological evolution of small organic molecular fluorescent probes for thiols, Chem. Sci., 2021, 12, 1220−1226.

6. Yongkang Yue, Fangjun Huo, Yuting Wang, Kaiqing Ma, Xiaoqing Li, Caixia Yin*, Mutual correlation evaluation of Cys and Hcy in serum through reaction activity regulated fluorescence quantification, Chem. Commun., 2020, 56, 9146−9149.

7. Yongkang Yue, Fangjun Huo, Xueying Pei, Yuting Wang, Caixia Yin*, Fluorescent imaging of resveratrol induced subcellular cysteine upregulation, Anal. Chem., 2020, 92, 6598−6603.

8. Yongkang Yue, Fangjun Huo, Fangqin Cheng, Xijing Zhu, Tendai Mafireyi, Robert M. Strongin*, Caixia Yin*, Functional synthetic probes for selective targeting and multi-analyte detection and imaging, Chem. Soc. Rev., 2019, 48, 4155−4177. （ESI高被引论文）

9. Yongkang Yue, Fangjun Huo, Caixia Yin*, Noradrenaline specific, efficient visualization in brain tissue triggered by unique ‘cascade’ nucleophilic substitution, Anal. Chem., 2019, 91, 2255−2259.

10. Yongkang Yue#, Fangjun Huo#, Ping Yue, Xiangming Meng, James C. Salamanca, Jorge O. Escobedo, Robert M. Strongin, Caixia Yin*, In situ lysosomal cysteine-specific targeting and imaging during dexamethasone induced apoptosis, Anal. Chem., 2018, 90, 7018−7024.

11. Yongkang Yue#, Fangjun Huo#, Peng Ning, Yongbin Zhang, Jianbin Chao, Xiangming Meng*, Caixia Yin*, Dual-site fluorescent probe for visualizing the metabolism of Cys in living cells, J. Am. Chem. Soc., 2017, 139, 3181−3185. （ESI高被引论文）

12. Yongkang Yue#, Fangjun Huo#, Xiaoqi Li, Ying Wen, Tao Yi*, James Salamanca, Jorge O. Escobedo, Robert M. Strongin*, Caixia Yin*, pH-Dependent fluorescent probe that can be tuned for cysteine or homocysteine, Org. Lett., 2017, 19, 82−85.

13. 岳永康, 霍方俊, 阴彩霞*, 硫醇亲核反应及其荧光识别研究, 中国科学: 化学, 2016, 47, 249–257.

14. Yongkang Yue, Fangjun Huo, Jianbin Chao, Yongbin Zhang, Ramón Martínez-Máñez*, Caixia Yin*, Curcumin-based “Enhanced SNAr” promoted ultrafast fluorescent probe for thiophenols detection in aqueous solution and in living cells, Anal. Chem., 2016, 88, 10499−10503.

15. Yongkang Yue, Fangjun Huo, Songyi Lee, Caixia Yin*, Juyoung Yoon*, Jianbin Chao, Yongbin Zhang, Fangqin Cheng*, A dual colorimetric/fluorescence system for determining pH based on the nucleophilic addition reaction of an o-hydroxymerocyanine dye, Chem. Eur. J., 2016, 22, 1239−1243.

联系方式：

地址：太原市坞城路92号

单位：山西大学分子科学研究所

邮编：030006

E-mail：ykyue@sxu.edu.cn