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王宏飞
[ 发布日期:2019-01-09  ] 【返回

王宏飞1969年生,教授,博士生导师1996毕业于中国南京大学获得理学博士学位2001毕业于日本立教大学获得理学博士学位2001年至2003年,在日本理化学研究所基因科学研究中心从事博士后研究。2003年至2009年,在日本理化学研究所生命分子系统研究领域任特别研究员。2012年入选山西省引进海外高层次人才百人计划2013年入选山西省高等院131领军人才工程,2014年入选山西省学术技术带头人。2015年入选中国生物医学光子学专业委员会委员2018年入选中国生物物理化学专业委员会委员。

 

研究兴趣和领域:生物无机化学,生物物理化学

 

近期发表论文:

1 Wenming Wang, Fengmei Zhao, Yarui Zhao, Weiwei Pan, Pengcheng Cao, Lintao Wu , Zhijun Wang, Xuan Zhao, Yi Zhao, Hongfei Wang*. Design, Synthesis, And Preliminary Bioactivity Evaluation Of 2,7-Substituted Carbazole Derivatives As Potent Autotaxin Inhibitors And Antitumor Agents. Anticancer Agents Med Chem. 2019, 2(19), 256-264.

2 Wenming Wang, Yao Zhang, Lele Wang, Qi Jing, Xiaolu Wang, Xiaoli Xi, Xuan Zhao, Hongfei Wang*. Molecular structure of thermostable and zinc-ion-binding r-class carbonic anhydrases. Biometals 2019, 32,317-328.

3 Xiaodong Cui, Tingfen Wang, Wenming Wang, Hongfei Wang, Zhuanhua Wang, Peroxidase from proso millet exhibits endonuclease-like activity. Acta Biochim Biophys Sin. 2019, 51(7), 688-696.

4 Wenming Wang, Lele Wang, Hai Chen, Jiacen Zang, Xuan Zhao, Guanghua Zhao, Hongfei Wang*. Selective Elimination of the Key Subunit Interfaces Facilitates Conversion of Native 24-mer Protein Nanocage into 8-mer Nanorings. J Am Chem Soc. 2018, 140, 14078-14081.

5 Kai Zhou, Jiacen Zang, Hai Chen, Wenming Wang, Hongfei Wang, Guaghua Zhao. On-Axis Alignment of Protein Nanocage Assemblies from 2D to 3D through the Aromatic Stacking Interactions of Amino Acid Residues. ACS Nano 2018, 12, 11323-11332.

6 Leilei Xie, Lifang Liu, Wenming Wang, Zhiou Ma, Liqun Xu, Xuan Zhao, Hongfei Wang*. The Structures, Spectroscopic Properties, and Photodynamic Reactions of Three [RuCl(QN)NO]2 Complexes (HQN = 8-Hydroxyquinoline and Its Derivatives) as Potential NO-Donating Drugs. Bioinorg Chem Appl., 2018, 7029376, 1-9.

7 Wenming Wang, Yaqin Zhao, Hongfei Wang*, and Bingsheng Yang. Crystal structure of the trimeric N-terminal domain of ciliate Euplotes octocarinatus centrin binding with calcium ions. Protein Sci. 2018, 27, 1102-1108.

8 Zhigang Zhang, Yantao Zhu, Ruihui Dai, Yinghong Zhang, Hongfei Wang, Jiangang Li. Enhanced photocytotoxicity induced by a platinum diimine complex employing amine-functionalized magnetite-silica nanocomposites as delivery vehicles, Photodiagnosis Photodyn Ther. 2018, 23, 50-54.

9 Liqun Xu, Zhiou Ma, Wenming Wang, Leilei Xie, Lifang Liu, Jiao Liu, Xuan Zhao, Hongfei Wang*. Photo-induced cytotoxicity, photo-controlled nitric oxide release and DNA/human serum albumin binding of three water-soluble nitrosylruthenium complexes, Polyhedron, 2017, 137, 157-164.

10 Xinyu Zhang, Wenming Wang, Chen Li, Yi Zhao, Hong Yuan, Xianshi Tan, Lijie Wu, Zhuanhua Wang, Hongfei Wang*. Structural insights into the binding of buckwheat glutaredoxin with GSH and regulation of its catalytic activity, Journal of Inorganic Biochemistry, 2017, 173, 21-27.

11 Shengli Zhang, Jiachen Zang, Wenming Wang, Hai Chen, Xiaorong Zhang, Fudi Wang, Hongfei Wang*, Guanghua Zhao. Conversion of Native 24-mer Ferritin Nanocage into Its Non-Native 16-mer Analogue by Insertion of Extra Amino Acid Residues. Angew. Chem. Int. Ed. 2016, 55, 16064 -16070.

12 Tomonari Muramatsu, Chie Takemoto, Yong-Tae Kim, Hongfei Wang, Wataru Nishii, Takaho Terada, Mikako Shirouzu, Shigeyuki Yokoyama. SARS-CoV 3CL protease cleaves its C-terminal autoprocessing site by novel subsite cooperativity. Proc Natl Acad Sci U. S. A. 2016, 113: 12997-13002.

13 Huifen Pan, Wenming Wang, Zhiou Ma, Liqun Xu, Zhigang Zhang, Yi Zhao, Xuan Zhao, Hongfei Wang*. Structures and spectroscopic properties of three [RuCl(2mqn)2NO] (H2mqn = 2-methyl-8-quinolinol) isomers: An experimental and density functional theoretical study, Polyhedron. 2016,118, 61-69.

14 Pengyun Yu, Yan Zhao, Fan Yang, Huifen Pan, Jianru Wang, Juan Zhao, Wenming Wang, Hongfei Wang, Jianping Wang. Differentiating Two Nitrosylruthenium Isomeric Complexes by Steady-State and Ultrafast Infrared Spectroscopies, J. Phys. Chem. B, 2016, 120, 11502-11509.

15 Yan Zhao, Fan Yang, Jianru Wang, Pengyun Yu, Huifen Pan, Hongfei Wang*, Jianping Wang. Structural dynamics of nitrosylruthenium isomeric complexes studied with steady-state and transient pump-probe infrared spectroscopies Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2016, 166: 62-67.

16 Jiao Liu, Qingqing Duan, Jianru Wang, Zhen Song, Xiaoyan Qiao, Hongfei Wang*. Photo-controlled NO release from two nitrosylruthenium isomer complexes and their potential biomedical applications, Journal of Biomedical Optics. 2015, 20(1), 015004.

17 Wei Li, Hongfei Wang, Cheng Lei, Tianlei Ying, Xiangshi Tan. Manganese superoxide dismutase from human pathogen Clostridium difficile. Amino Acids. 2015, 47, 987-995.

18 Jianru Wang, Huifen Pan, Jiao Liu, Yan Zhao, Yanbo Wu, Hongfei Wang*. Structures and spectroscopic properties of three [Ru(OAc)(2mqn)2NO](H2mqn=2-methyl-8-quinolinol) isomers: An experimental and density functional theoretical insight. Journal of Molecular Structure 10086, 232-238, 2015.

19 Zhigang Zhang, Ruihui Dai, Jiajia Ma, Shuying Wang, Xuehong Wei, HongfeiWang. Photoinduced DNA damage and cytotoxicity by a triphenylamine-modified platinum-diimine complex. Journal of Inorganic Biochemistry, 143, 64–68, 2015.

20 Jianru Wang, Fan Yang, Yan Zhao, Pengyun Yu, Xiaoyan Qiao, Jianping Wang, Hongfei Wang*. Photoisomerization and Structural Dynamics of Two Nitrosylruthenium Complexes: A Joint Study by NMR and Nonlinear IR Spectroscopies, Phys. Chem. Chem. Phys. 16, 24045-24054, 2014.

21 Wei Li, Hongfei Wang, Qingli Wang and Xiangshi Tan, Structural, spectroscopic and functional investigation into Fe-substituted MnSOD from human pathogen Clostridium difficile, Metallomics, 6, 1540-1548, 2014.

22 Wei Li, Hongfei Wang, Zheng Chen, Qing Ye, Yang Tian, Xin Xu, Zhongxian Huang, Pingwei Li, Xiangshi Tan. Probing the metal specificity mechanism of superoxide dismutase from human pathogen Clostridium difficile, Chem. Commun. 50, 584-586, 2014.

23 Jianru Wang, Yan Zhao, Xiaowei Jin, Li Yang, Hongfei Wang*. Structural, electronic, vibrational and NMR spectral analyses of [Ru(OAc)(2cqn)2NO] (H2cqn=2-chloro-8-quinolinol) isomers, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 122, 649–655, 2014.


联系方式:
地址:太原市坞城路92
单位:山西大学分子科学研究所
邮编:030006
手机:158-3401-1037
E-mail: wanghf@sxu.edu.cn


友情链接: 北京大学 清华大学 南京大学 中科院山西煤化所 太原理工大学 中北大学
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